Knee Cartilage
Demo Author One
Cartilage repair options for lasting joint health
A practical overview of cartilage repair, injection therapy, rehabilitation planning, and the clinical evidence that guides joint preservation care.
Regenerative injections compared
Mytocel MSK vs mFat (Microfragmented Fat)
mFat draws regenerative cells from your own fat; Mytocel MSK prepares micrografts from a small tissue sample. Both are single-session and autologous. Here is how they differ.
Reviewed byProfessor Paul Lee MBBch, FRCS (Tr & Orth), PhDCartilage and joint preservation expertiseQuick answer
Both draw regenerative cells from your own body, from different tissue. mFat (microfragmented fat) takes a sample of your own fat, processes it, and injects the microfragmented tissue with the regenerative cells it holds. Mytocel MSK instead prepares living micrografts chair-side from a small sample of your own tissue. Both are single-session autologous injections with no laboratory culture; they differ in the source tissue and how it is prepared. mFat is from £5,800; Mytocel MSK is from £3,000.
Both are genuine options at London Cartilage Clinic. mFat draws a larger volume of regenerative cells from your fat and suits some joints; Mytocel MSK is a smaller, chair-side micrograft approach.
mFat vs Mytocel MSK at a glance
| What to compare | mFat / microfragmented fat | Mytocel MSK |
|---|---|---|
| Source tissue | A sample of your own fat, usually from the abdomen or flank | A small sample of your own tissue |
| How it is prepared | Fat is microfragmented and washed, then injected | Tissue is processed chair-side into living micrografts |
| What it delivers | A larger volume of regenerative cells held in fat tissue | Living micrografts rich in your own progenitor cells and their matrix |
| Laboratory culture | None | None |
| Sessions | One | One |
| Best suited to | Some joints, where a larger volume of fat-derived cells is wanted | Earlier joint wear, with a smaller chair-side micrograft |
| Autologous (your own tissue) | Yes | Yes |
| Available at London Cartilage Clinic | Yes, from £5,800 | Yes, from £3,000 |
Both injections are offered at London Cartilage Clinic; this is a genuine choice, not a takedown of mFat.
When mFat may be the better choice
- A larger volume of regenerative cells drawn from your own fat suits your joint.
- Your surgeon judges fat-derived tissue is a good match for the area being treated.
- You are comfortable with a fat sample as the source of the regenerative cells.
- The plan calls for the greater cell volume that fat tissue can provide, from £5,800.
When Mytocel MSK is the better choice
- You would prefer a smaller, chair-side micrograft prepared from a small tissue sample.
- Your joint wear is earlier, where a lighter-touch micrograft approach fits well.
- You want a single-session, autologous injection at a lower cost, from £3,000.
- You are considering NanoACi, where the same Mytocel MSK micrografts are the cell component.
Both mFat and Mytocel MSK are genuine, autologous regenerative injections, and both are offered here, so this is an honest comparison rather than a takedown. mFat draws a larger volume of regenerative cells from a sample of your own fat, which suits some joints well. Mytocel MSK takes a different route, preparing living micrografts chair-side from a small tissue sample, a smaller-scale approach that is well matched to earlier wear. The right choice depends on your joint, the tissue source that suits you and your imaging, which is exactly what the consultation is for. Cost differs too: mFat is from £5,800 and Mytocel MSK is from £3,000.
Frequently Asked Questions
What is the difference between mFat and Mytocel MSK?
mFat (microfragmented fat) takes a sample of your own fat, microfragments and washes it, then injects the tissue with the regenerative cells it holds. Mytocel MSK prepares living micrografts chair-side from a small sample of your own tissue. Both are single-session autologous injections with no laboratory culture; they differ in the source tissue and how it is prepared.
Is microfragmented fat better than Mytocel MSK?
Neither is simply better. mFat provides a larger volume of regenerative cells drawn from your fat and suits some joints, at from £5,800. Mytocel MSK is a smaller, chair-side micrograft approach well matched to earlier wear, at from £3,000. The right choice depends on your joint and the tissue source that suits you, decided on imaging and examination.
Are both mFat and Mytocel MSK made from my own tissue?
Yes. Both are autologous. mFat comes from a sample of your own fat, and Mytocel MSK micrografts are prepared from a small sample of your own tissue. Neither uses donor material and nothing is grown in a laboratory. Mytocel MSK is made by Remedi on their Regenera Activa micrografting system.
How much do mFat and Mytocel MSK cost at London Cartilage Clinic?
mFat is from £5,800 and Mytocel MSK is from £3,000. Your exact plan and cost are confirmed at consultation, once Professor Lee has reviewed your imaging.
Which one is right for my joint?
That depends on the joint, the tissue source that suits you and your imaging. mFat can be a good fit where a larger volume of fat-derived cells is wanted; Mytocel MSK suits earlier wear with a smaller chair-side micrograft. Because both are offered here, Professor Lee can choose honestly rather than fitting you to one product. See the Mytocel MSK page.
Still have more specific concerns?
Free Discovery CallOptions that our doctors may discuss include NanoACi, ChondroFiller, Mytocel MSK, joint replacement, established conservative care or surgery, depending on examination and imaging.
mFat or Mytocel MSK: let us review your scan.
Because we offer both, the fairest next step is a review of your imaging and examination. Start with a free discovery call, or book a consultation with Professor Lee.
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