Clinician preparing a regenerative cartilage injection

NanoACi cost in the UK

NanoACi is Professor Paul Lee’s injection protocol for cartilage regeneration, delivering your own cells, a ChondroFiller scaffold and PRF in a single session, without surgery. It is £8,000, or £8,500 all-inclusive of an MRI scan, your consultation, the session and one follow-up. Available for the knee, hip, shoulder and ankle, with no upper age limit.
  • ICRS Teaching Centre of Excellence
  • Single session, no surgery
  • 173+ verified patient reviews
ICRS Teaching Centre of ExcellenceSingle session, no surgery173+ verified patient reviews

At a glance

How much does NanoACi cost in the UK?

NanoACi costs £8,000 at London Cartilage Clinic, or £8,500 all-inclusive, which covers an MRI scan, your consultation with Professor Lee, the single-session NanoACi injection and one follow-up. Booking the MRI and appointment together is the simplest way to start, so your imaging is ready when you are seen. The same pricing applies across the knee, hip, shoulder and ankle.

Most patients choose the all-inclusive pathway so the MRI, consultation, session and follow-up are settled as one.

ProcedurePrice

NanoACi

The single-session injection protocol on its own.

£8,000

NanoACi, all-inclusive

MRI scan, consultation, the session and one follow-up.

£8,500
Last reviewed April 2026. The all-inclusive price covers the MRI scan, consultation, the NanoACi session and one follow-up. Same pricing across the knee, hip, shoulder and ankle.

NanoACi cost in the UK explained

NanoACi brings together three of your own tissues in one appointment: your cartilage cells, prepared with the Mytocel MSK micrografting technique, a ChondroFiller collagen scaffold, and PRF prepared from your own blood on the day. Preparing and delivering all three in a single sequenced session is the work behind the price. There is no laboratory culture and nothing is grown over weeks, which is what keeps this a one-visit treatment rather than surgery.

At London Cartilage Clinic the protocol is performed by Professor Paul Lee. The all-inclusive figure folds in the MRI scan and the follow-up so there is nothing to add on top. We do not quote the imaging, the consultation and the session as separate fees to be totalled later.

What the all-inclusive price includes

Included in the price

  • An MRI scan, where you do not already have one from the last six months
  • Consultation with Professor Lee and an imaging review
  • The single-session NanoACi injection under local anaesthetic
  • Your own cells prepared with the Mytocel MSK technique, plus the ChondroFiller scaffold and PRF
  • On-the-day medications including local anaesthetic
  • One follow-up appointment
  • A direct line to the team for questions during recovery

Not included, quoted separately

  • Onward physiotherapy, which is quoted separately by your physiotherapist
  • An Arthrosamid injection, where this is added for advanced, bone-on-bone wear
  • Travel and accommodation for international patients

Why NanoACi at London Cartilage Clinic

  • Professor Lee’s own protocol

    NanoACi is a technique Professor Paul Lee developed and performs. It is not a product or device bought off a shelf; it is his way of delivering your own cells, scaffold and PRF in one session, refined for each joint.
  • ICRS Teaching Centre of Excellence

    London Cartilage Clinic is recognised by the International Cartilage Regeneration and Joint Preservation Society as a Teaching Centre of Excellence, with one of the largest published cartilage outcome databases in Europe.
  • A regenerate-first philosophy

    NanoACi fits a philosophy that prefers preserving and regenerating your own joint over replacing it. Even bone-on-bone wear does not rule it out; it is often paired with an Arthrosamid injection rather than sent straight to replacement.
  • One session, no theatre

    The whole treatment is a single outpatient appointment of around thirty minutes under local anaesthetic. Most people return to light daily activity the same day.

Your NanoACi journey

  1. 1

    Discovery call (free, 15 minutes)

    A clinical coordinator confirms whether NanoACi looks like the right treatment to investigate and answers cost questions.
  2. 2

    MRI and consultation

    If you have had an MRI in the last six months, bring it. If not, we arrange your scan and consultation together, so Professor Lee can review your imaging and plan treatment in one visit.
  3. 3

    The NanoACi session

    A single 30-minute outpatient appointment under local anaesthetic. No general anaesthetic and no theatre. Most patients go home the same day.
  4. 4

    First week

    Rest the joint for the first week and keep the small ear donor site clean. Most people are back to light daily activity the same day.
  5. 5

    Follow-up

    A follow-up appointment is included. Improvement usually starts between two and six weeks.

Funding, insurance and payment

Self-pay

£8,000 for the session, or £8,500 all-inclusive, settled by bank transfer or card before treatment.

We can discuss finance options on request. We do not actively promote a specific finance partner.

Private medical insurance

London Cartilage Clinic is a private-pay practice and does not work with UK insurance panels. NanoACi is not routinely available on the NHS or via the major UK insurers.

We can provide an itemised invoice for you to submit to your insurer if you wish to claim the treatment back; the agreement is between you and your insurer.

International patients

Patients travel from outside the UK for NanoACi. We can coordinate the MRI, consultation and session into a focused visit; travel and accommodation are arranged separately.

Outcomes after NanoACi

NanoACi is a regenerative protocol, not an immediate symptom-relief injection. Most patients notice less pain and stiffness between two and six weeks. In studies of the auricular micrografting technology behind the Mytocel MSK step, benefit has been reported to last at least three years from a single session. Those figures describe the technology, not London Cartilage Clinic’s own case numbers.

Professor Lee will explain, in writing at consultation, what the evidence does and does not yet show for your particular joint. As with any newer combination, the strongest evidence sits with each component, and outcomes for the protocol are reviewed case by case.

Patient stories

I wanted to avoid surgery if I possibly could. The injection took half an hour and I walked out the same afternoon. A few weeks on, the joint feels calmer than it has in years.
Verified patient, Doctify

Frequently asked questions

How much does NanoACi cost in the UK?

NanoACi at London Cartilage Clinic is £8,000, or £8,500 all-inclusive of the MRI scan, consultation, the session and one follow-up. The same pricing applies across the knee, hip, shoulder and ankle.

What does the all-inclusive price cover?

The £8,500 figure covers an MRI scan (where you do not already have a recent one), your consultation with Professor Lee, the single-session NanoACi injection and one follow-up. Onward physiotherapy is quoted separately.

Do I need to pay for an MRI on top?

Not on the all-inclusive pathway. If you have had an MRI in the last six months, bring it and you may not need another. If not, the scan is included in the £8,500 all-inclusive price, arranged together with your appointment.

Is NanoACi covered by insurance or the NHS?

London Cartilage Clinic is a private-pay practice and does not contract with UK insurance panels. NanoACi is not routinely available on the NHS. We can provide an itemised invoice if you wish to submit a claim independently.

I have been told I am bone-on-bone. Will it cost more?

Bone-on-bone wear does not rule NanoACi out. In that situation Professor Lee will usually discuss pairing NanoACi with an Arthrosamid injection, which is quoted separately, or a joint replacement review. What suits you is decided on examination and imaging.

Can I pay in instalments?

We can discuss finance options on request rather than promoting a specific provider. The treatment is also straightforward to settle by bank transfer or card before the session.

Is the clinician I see at consultation the same one who treats me?

Yes. Professor Paul Lee reviews your imaging at consultation and performs the NanoACi session himself. There is no transfer to a less experienced clinician.

Ready to talk

Two paths from here

For when you want to talk first, the discovery call costs nothing. For when you have decided you want to be assessed, book a consultation with the operating surgeon. Either way you can learn how the procedure works on the NanoACi page.

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